A model of Notch signalling control of angiogenesis: Evidence of a role for Notch ligand heterodimerization.
The ubiquitous Notch receptor signalling network is essential for tissue growth and maintenance. Operationally, receptor activity is regulated by two principal, counterposed mechanisms: intercellular Notch transactivation triggered by interactions between receptors and ligands expressed in neighbour...
Main Authors: | , , , , |
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פורמט: | Article |
שפה: | English |
יצא לאור: |
Public Library of Science (PLoS)
2025-02-01
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סדרה: | PLoS Computational Biology |
גישה מקוונת: | https://doi.org/10.1371/journal.pcbi.1012825 |