A model of Notch signalling control of angiogenesis: Evidence of a role for Notch ligand heterodimerization.

The ubiquitous Notch receptor signalling network is essential for tissue growth and maintenance. Operationally, receptor activity is regulated by two principal, counterposed mechanisms: intercellular Notch transactivation triggered by interactions between receptors and ligands expressed in neighbour...

תיאור מלא

מידע ביבליוגרפי
Main Authors: Daipeng Chen, Xinxin Liu, Haijiang Wang, Roeland M H Merks, David A Baker
פורמט: Article
שפה:English
יצא לאור: Public Library of Science (PLoS) 2025-02-01
סדרה:PLoS Computational Biology
גישה מקוונת:https://doi.org/10.1371/journal.pcbi.1012825