Inhibitory effect of Selaginella doederleinii hieron on human cytochrome P450

Inhibitory effect of Selaginella doederleinii hieron on human cytochrome P450

Introduction:Selaginella doederleinii Hieron is a traditional Chinese herbal medicine, the ethyl acetate extract from Selaginella doederleinii (SDEA) showed favorable anticancer potentials. However, the effect of SDEA on human cytochrome P450 enzymes (CYP450) remains unclear. To predict the herb-dru...

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Bibliographic Details
Main Authors: Fei Lin, Xinhua Lin, Xuewen Wang, Guanghui Mei, Bing Chen, Hong Yao, Lingyi Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Pharmacology
Subjects:
herb-drug interaction
the ethyl acetate extract from S. doederleinii
CYP inhibition
cocktail CYP450 assay
time > dependent inhibition
delicaflavone
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1108867/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1108867/full

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