Direct Interaction between Carcinoma Cells and Cancer Associated Fibroblasts for the Regulation of Cancer Invasion

The tumor stroma acts as an essential microenvironment of the cancer cells, which includes many different types of non-cancerous cells and the extracellular matrix (ECM). Stromal fibroblasts (SFs) are the major cellular constituents of the tumor stroma and are often called cancer-associated fibrobla...

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Bibliographic Details
Main Authors: Hideki Yamaguchi, Ryuichi Sakai
Format: Article
Language:English
Published: MDPI AG 2015-10-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/7/4/0876