A twist defect mechanism for ATP-dependent translocation of nucleosomal DNA

A twist defect mechanism for ATP-dependent translocation of nucleosomal DNA

As superfamily 2 (SF2)-type translocases, chromatin remodelers are expected to use an inchworm-type mechanism to walk along DNA. Yet how they move DNA around the histone core has not been clear. Here we show that a remodeler ATPase motor can shift large segments of DNA by changing the twist and leng...

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Bibliographic Details
Main Authors: Jessica Winger, Ilana M Nodelman, Robert F Levendosky, Gregory D Bowman
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-05-01
Series:eLife
Subjects:
nucleosome
chromatin remodeling
superfamily 2 ATPase
DNA translocation
twist defect
Snf2 ATPase
Online Access:https://elifesciences.org/articles/34100

Internet

https://elifesciences.org/articles/34100

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