Multifaceted glycoadjuvant@AuNPs inhibits tumor metastasis through promoting T cell activation and remodeling tumor microenvironment

Abstarct Background Cytosine-phosphate-guanine (CpG) dinucleotides has been used as adjuvants for cancer immunotherapy. However, unmodified CpG are not very efficient in clinical trials. Glucose, ligand of C-type lectin receptors (CLRs), can promote DC maturation and antigen presentation, which is t...

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Bibliographic Details
Main Authors: Xiaojing Xu, Minfeng Gan, Youzhen Ge, Cheng Yi, Tianyun Feng, Mengjie Liu, Cenhao Wu, Xiang Chen, Weidong Zhang, Lixiang Zhao, Jun Zou
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Journal of Nanobiotechnology
Online Access:https://doi.org/10.1186/s12951-021-01129-3