Id2 promotes the invasive growth of MCF-7 and SKOV-3 cells by a novel mechanism independent of dimerization to basic helix-loop-helix factors

<p>Abstract</p> <p>Background</p> <p>Inhibitor of differentiation 2 (<it>Id2</it>) is a critical factor for cell proliferation and differentiation in normal vertebrate development. Most of the biological function of Id2 has been ascribed to its helix-loop-he...

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Bibliographic Details
Main Authors: Si Yiling, Zhao Yali, Wu Zhiqiang, Gu Chenglei, Meng Yuanguang, Fu Xiaobing, Han Weidong
Format: Article
Language:English
Published: BMC 2009-03-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/9/75