Exploiting the mediating role of the metabolome to unravel transcript-to-phenotype associations

Despite the success of genome-wide association studies (GWASs) in identifying genetic variants associated with complex traits, understanding the mechanisms behind these statistical associations remains challenging. Several methods that integrate methylation, gene expression, and protein quantitative...

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Bibliographic Details
Main Authors: Chiara Auwerx, Marie C Sadler, Tristan Woh, Alexandre Reymond, Zoltán Kutalik, Eleonora Porcu
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-03-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/81097