Circularity of islets is a distinct marker for the pathological diagnosis of adult non-neoplastic hyperinsulinemic hypoglycemia using surgical specimens

Circularity of islets is a distinct marker for the pathological diagnosis of adult non-neoplastic hyperinsulinemic hypoglycemia using surgical specimens

Abstract Background Adult non-neoplastic hyperinsulinemic hypoglycemia (ANHH), also known as adult-onset nesidioblastosis, is a rare cause of endogenous hyperinsulinemic hypoglycemia in adults. This disease is characterized by diffuse hyperplasia of pancreatic endocrine cells and is diagnosed by a p...

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Bibliographic Details
Main Authors: Ryota Nakagawa, Sachiko Minamiguchi, Tatsuki R. Kataoka, Junji Fujikura, Toshihiko Masui, Masakazu Fujimoto, Yosuke Yamada, Yasuhide Takeuchi, Yuki Teramoto, Hiroaki Ito, Manduwa Saka, Kyohei Kitamura, Shinya Otsuki, Ryohei Nishijima, Hironori Haga
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Diagnostic Pathology
Subjects:
Adult non-neoplastic hyperinsulinemic hypoglycemia (ANHH)
Circularity
Digital pathology
Image analysis
Islets
Nesidioblastosis
Online Access:https://doi.org/10.1186/s13000-023-01403-y

Internet

https://doi.org/10.1186/s13000-023-01403-y

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