Characterization of a murine model of endothelial dysfunction induced by chronic intraperitoneal administration of angiotensin II

Abstract Endothelial dysfunction (ED) is a key factor for the development of cardiovascular diseases. Due to its chronic, life-threatening nature, ED only can be studied experimentally in animal models. Therefore, this work was aimed to characterize a murine model of ED induced by a daily intraperit...

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Bibliographic Details
Main Authors: Celeste Trejo-Moreno, Enrique Jiménez-Ferrer, Gabriela Castro-Martínez, Marisol Méndez-Martínez, María Angélica Santana, Gerardo Arrellín-Rosas, José Pedraza-Chaverri, Omar Noel Medina-Campos, Beatriz Hernández-Téllez, Oscar Ramírez-Pliego, Maribel Herrera-Ruiz, Jacquelynne Cervantes-Torres, Zimri Aziel Alvarado-Ojeda, Alejandro Costet-Mejía, Gladis Fragoso, Gabriela Rosas-Salgado
Format: Article
Language:English
Published: Nature Portfolio 2021-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-00676-x