Complement, Coagulation, and Fibrinolysis: The Role of the Endothelium and Its Glycocalyx Layer in Xenotransplantation

In xenotransplantation, the vascular endothelium serves as the first point of contact between the recipient’s blood and the transplanted donor organ. The loss of the endothelium’s ability to control the plasma cascades plays a critical role in the dysregulation of the complement and coagulation syst...

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Bibliographic Details
Main Authors: Mitra Gultom, Robert Rieben
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Transplant International
Subjects:
Online Access:https://www.frontierspartnerships.org/articles/10.3389/ti.2024.13473/full