Anti‐N‐homocysteine‐protein autoantibodies are associated with impaired cognition

Abstract Introduction Elevated homocysteine (Hcy) and related metabolites accelerate Alzheimer's disease. Hcy‐lowering B vitamins slow brain atrophy/cognitive decline in mild cognitive impairment (MCI). Modification with Hcy‐thiolactone generates auto‐immunogenic N‐Hcy‐protein. We tested a hypo...

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Bibliographische Detailangaben
Hauptverfasser: Olga Włoczkowska, Joanna Perła‐Kaján, A. David Smith, Celeste deJager, Helga Refsum, Hieronim Jakubowski
Format: Artikel
Sprache:English
Veröffentlicht: Wiley 2021-01-01
Schriftenreihe:Alzheimer’s & Dementia: Translational Research & Clinical Interventions
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Online Zugang:https://doi.org/10.1002/trc2.12159