Direct Derivatization in Dried Blood Spots for Oxidized and Reduced Glutathione Quantification in Newborns

Direct Derivatization in Dried Blood Spots for Oxidized and Reduced Glutathione Quantification in Newborns

The glutathione (GSH)-to-glutathione disulfide (GSSG) ratio is an essential node contributing to intracellular redox status. GSH/GSSG determination in whole blood can be accomplished by liquid chromatography–mass spectrometry (LC-MS) after the derivatization of GSH with <i>N</i>-ethylmal...

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Bibliographic Details
Main Authors: Isabel Ten-Doménech, Álvaro Solaz-García, Inmaculada Lara-Cantón, Alejandro Pinilla-Gonzalez, Anna Parra-Llorca, Máximo Vento, Guillermo Quintás, Julia Kuligowski
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Antioxidants
Subjects:
redox status
oxidative stress
dried blood spot
liquid chromatography–mass spectrometry (LC-MS)
Online Access:https://www.mdpi.com/2076-3921/11/6/1165

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https://www.mdpi.com/2076-3921/11/6/1165

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