Chronic, Elevated Maternal Corticosterone During Pregnancy in the Mouse Increases Allergic Airway Inflammation in Offspring

Chronic, Elevated Maternal Corticosterone During Pregnancy in the Mouse Increases Allergic Airway Inflammation in Offspring

Allergic asthma is a chronic pulmonary disorder fundamentally linked to immune dysfunction. Since the immune system begins developing in utero, prenatal exposures can affect immune programming and increase risk for diseases such as allergic asthma. Chronic psychosocial stress during pregnancy is one...

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Bibliographic Details
Main Authors: Arianna L. Smith, Emmanuel Paul, Devin McGee, Ranuka Sinniah, Emily Flom, Devan Jackson-Humbles, Jack Harkema, Karen E. Racicot
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Immunology
Subjects:
stress
pregnancy
prenatal programming
allergic inflammation
asthma
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.03134/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.03134/full

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