DNA Damage Repair Profiles Alteration Characterize a Hepatocellular Carcinoma Subtype With Unique Molecular and Clinicopathologic Features

DNA Damage Repair Profiles Alteration Characterize a Hepatocellular Carcinoma Subtype With Unique Molecular and Clinicopathologic Features

Hepatocellular carcinoma (HCC) is one of the most common malignancies and displays high heterogeneity of molecular phenotypes. We investigated DNA damage repair (DDR) alterations in HCC by integrating multi-omics data. HCC patients were classified into two heterogeneous subtypes with distinct clinic...

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Bibliographic Details
Main Authors: Peng Lin, Rui-zhi Gao, Rong Wen, Yun He, Hong Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
hepatocellular carcinoma
DNA damage repair
multi-omics
immune
survival
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.715460/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.715460/full

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