Insertion site of FLAG on foot-and-mouth disease virus VP1 G-H loop affects immunogenicity of FLAG

Insertion site of FLAG on foot-and-mouth disease virus VP1 G-H loop affects immunogenicity of FLAG

The G-H loop of the foot-and-mouth disease virus (FMDV) virion contains certain dominant immunogenic epitopes, as well as an arginine-glycine-aspartic acid (RGD) motif that is recognized by cell surface integrin receptors. Previous experiments indicate that it is critical to maintain virus structura...

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Bibliographic Details
Main Authors: Yuan-yuan ZHU, Xing-qi ZOU, Hui-fang BAO, Pu SUN, Xue-qing MA, Zai-xin LIU, Hong-jie FAN, Qi-zu ZHAO
Format: Article
Language:English
Published: Elsevier 2018-07-01
Series:Journal of Integrative Agriculture
Subjects:
FMDV
G-H loop
insertion sites
FLAG-tagged viruses
reverse genetics
Online Access:http://www.sciencedirect.com/science/article/pii/S2095311918619161

Internet

http://www.sciencedirect.com/science/article/pii/S2095311918619161

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