High Level Expression of MHC-II in HPV+ Head and Neck Cancers Suggests that Tumor Epithelial Cells Serve an Important Role as Accessory Antigen Presenting Cells

High Level Expression of MHC-II in HPV+ Head and Neck Cancers Suggests that Tumor Epithelial Cells Serve an Important Role as Accessory Antigen Presenting Cells

High-risk human papillomaviruses (HPVs) are responsible for a subset of head and neck squamous cell carcinomas (HNSCC). Expression of class II major histocompatibility complex (MHC-II) is associated with antigen presenting cells (APCs). During inflammation, epithelial cells can be induced to express...

Full description

Bibliographic Details
Main Authors: Steven F. Gameiro, Farhad Ghasemi, John W. Barrett, Anthony C. Nichols, Joe S. Mymryk
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cancers
Subjects:
human papillomavirus
MHC-II
major histocompatibility complex
antigen presentation
head and neck carcinoma
co-stimulatory molecules
survival signals
T-cell
Online Access:https://www.mdpi.com/2072-6694/11/8/1129

Internet

https://www.mdpi.com/2072-6694/11/8/1129

Similar Items