MicroRNA-223 demonstrated experimentally in exosome-like vesicles is associated with decreased risk of persistent pain after lumbar disc herniation

MicroRNA-223 demonstrated experimentally in exosome-like vesicles is associated with decreased risk of persistent pain after lumbar disc herniation

Abstract Background Previous findings have demonstrated that lumbar radicular pain after disc herniation may be associated with up-regulation of inflammatory mediators. In the present study we examined the possible role of extracellular microRNAs (miRs) in this process. Methods Single unit recording...

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Bibliographic Details
Main Authors: Aurora Moen, Daniel Jacobsen, Santosh Phuyal, Anna Legfeldt, Fred Haugen, Cecilie Røe, Johannes Gjerstad
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Journal of Translational Medicine
Subjects:
Lumbar radicular pain
Disc herniation
Inflammation
Immune response
microRNA-223
miR-223
Online Access:http://link.springer.com/article/10.1186/s12967-017-1194-8

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http://link.springer.com/article/10.1186/s12967-017-1194-8

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