The Prognostic and therapeutic value and clinical implications of fibroblast activation protein-α as a novel biomarker in colorectal cancer

Abstract The identification of contributing factors leading to the development of Colorectal Cancer (CRC), as the third fatal malignancy, is crucial. Today, the tumor microenvironment has been shown to play a key role in CRC progression. Fibroblast-Activation Protein-α (FAP) is a type II transmembra...

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Bibliographic Details
Main Authors: Zahra Kalaei, Reyhaneh Manafi-Farid, Bentolhoda Rashidi, Fariba Karoon Kiani, Asieh Zarei, Mehrdad Fathi, Farhad Jadidi-Niaragh
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Cell Communication and Signaling
Subjects:
Online Access:https://doi.org/10.1186/s12964-023-01151-y