M. tuberculosis AlkX Encoded by rv3249c Regulates a Conserved Alkane Hydroxylase System That Is Important for Replication in Macrophages and Biofilm Formation

M. tuberculosis AlkX Encoded by rv3249c Regulates a Conserved Alkane Hydroxylase System That Is Important for Replication in Macrophages and Biofilm Formation

ABSTRACT Mycobacterium tuberculosis is a highly specialized human pathogen. The success of M. tuberculosis is due to its ability to replicate within host macrophages, resist host immune responses, and ultimately enter a persistent state during a latent tuberculosis infection. Understanding how M. tu...

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Bibliographic Details
Main Authors: Haley Stokas, Heather L. Rhodes, Marit B. Simmons, Richard Zhang, Catherine C. Wright, Georgiana E. Purdy
Format: Article
Language:English
Published: American Society for Microbiology 2022-08-01
Series:Microbiology Spectrum
Subjects:
Mycobacterium tuberculosis
transcription factor
alkane hydroxylase
rubredoxin
biofilm
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01969-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.01969-22

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