Toll-Like Receptor 3 Signaling via TRIF Contributes to a Protective Innate Immune Response to Severe Acute Respiratory Syndrome Coronavirus Infection

Toll-Like Receptor 3 Signaling via TRIF Contributes to a Protective Innate Immune Response to Severe Acute Respiratory Syndrome Coronavirus Infection

ABSTRACT Toll-like receptors (TLRs) are sensors that recognize molecular patterns from viruses, bacteria, and fungi to initiate innate immune responses to invading pathogens. The emergence of highly pathogenic coronaviruses severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East res...

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Bibliographic Details
Main Authors: Allison L. Totura, Alan Whitmore, Sudhakar Agnihothram, Alexandra Schäfer, Michael G. Katze, Mark T. Heise, Ralph S. Baric
Format: Article
Language:English
Published: American Society for Microbiology 2015-07-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00638-15

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https://journals.asm.org/doi/10.1128/mBio.00638-15

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