Neuronal Menin Overexpression Rescues Learning and Memory Phenotype in CA1-Specific α7 nAChRs KD Mice

Neuronal Menin Overexpression Rescues Learning and Memory Phenotype in CA1-Specific α7 nAChRs KD Mice

The perturbation of nicotinic cholinergic receptors is thought to underlie many neurodegenerative and neuropsychiatric disorders, such as Alzheimer’s and schizophrenia. We previously identified that the tumor suppressor gene, <i>MEN1</i>, regulates both the expression and synaptic target...

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Bibliographic Details
Main Authors: Shadab Batool, Basma Akhter, Jawwad Zaidi, Frank Visser, Gavin Petrie, Matthew Hill, Naweed I. Syed
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Cells
Subjects:
learning and memory
nicotinic cholinergic receptors
menin
synaptogenesis
extracellular activity
brain connectivity
Online Access:https://www.mdpi.com/2073-4409/10/12/3286

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https://www.mdpi.com/2073-4409/10/12/3286

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