Dimorphic glioblastoma with glial and epithelioid phenotypes: Clonal evolution and immune selection

Dimorphic glioblastoma with glial and epithelioid phenotypes: Clonal evolution and immune selection

PurposeEpithelioid glioblastoma is an unusual histologic variant of malignant glioma. The present study investigates both the genomic and transcriptomic determinants that may promote the development of this tumor.MethodsWhole-exome sequencing (WES) and whole-transcriptome sequencing (WTS) were perfo...

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Bibliographic Details
Main Authors: Mark Willy L. Mondia, Michael A. Kritselis, John E. Donahue, Heinrich Elinzano, Sasmit Sarangi, David Bryant, Marzia Capelletti, W. Michael Korn, Esther Yu, Sherry Yan, Steven A. Toms, Eric T. Wong
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Neurology
Subjects:
epithelioid glioblastoma
exome sequencing
immune profiling glioblastoma with glial and epithelioid phenotypes
malignant glioma
clonal evaluation
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2022.1017087/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2022.1017087/full

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