PCNA Ser46-Leu47 residues are crucial in preserving genomic integrity.

PCNA Ser46-Leu47 residues are crucial in preserving genomic integrity.

Proliferating cell nuclear antigen (PCNA) is a maestro of DNA replication. PCNA forms a homotrimer and interacts with various proteins, such as DNA polymerases, DNA ligase I (LIG1), and flap endonuclease 1 (FEN1) for faithful DNA replication. Here, we identify the crucial role of Ser46-Leu47 residue...

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Bibliographic Details
Main Authors: Sangin Kim, Yeongjae Kim, Youyoung Kim, Suhyeon Yoon, Kyoo-Young Lee, Yoonsung Lee, Sukhyun Kang, Kyungjae Myung, Chang-Kyu Oh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0285337

Internet

https://doi.org/10.1371/journal.pone.0285337

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