Measurement of Autophagy Activity Reveals Time-Dependent, Bacteria-Specific Turnover during <i>Mycobacterium tuberculosis</i> Infection

Measurement of Autophagy Activity Reveals Time-Dependent, Bacteria-Specific Turnover during <i>Mycobacterium tuberculosis</i> Infection

The intracellular pathogen, <i>Mycobacterium tuberculosis</i> (M. tb) uses various mechanisms to evade its killing. One of such is phagosomal damage and cytosolic translocation which is then targeted by the host’s bactericidal autophagy pathway. It is suggested that cytosolic translocati...

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Bibliographic Details
Main Authors: Naomi Okugbeni, André du Toit, Victoria Cole-Holman, Glynis Johnson, Ben Loos, Craig Kinnear
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Pathogens
Subjects:
autophagic flux
autophagy turnover
biomarker
immunofluorescence microscopy
LC3B
p62
Online Access:https://www.mdpi.com/2076-0817/12/1/24

Internet

https://www.mdpi.com/2076-0817/12/1/24

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