Modulation of the Response to Mycobacterium leprae and Pathogenesis of Leprosy

Modulation of the Response to Mycobacterium leprae and Pathogenesis of Leprosy

The initial infection by the obligate intracellular bacillus Mycobacterium leprae evolves to leprosy in a small subset of the infected individuals. Transmission is believed to occur mainly by exposure to bacilli present in aerosols expelled by infected individuals with high bacillary load. Mycobacte...

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Bibliographic Details
Main Authors: Natasha Cabral, Vilma de Figueiredo, Mariana Gandini, Cíntia Fernandes de Souza, Rychelle Affonso Medeiros, Letícia Miranda Santos Lery, Flávio Alves Lara, Cristiana Santos de Macedo, Maria Cristina Vidal Pessolani, Geraldo Moura Batista Pereira
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Microbiology
Subjects:
leprosy pathogenesis
memory T cells
regulatory T cells
lipid droplets
polyunsaturated fatty acid metabolites
interferon-γ
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.918009/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2022.918009/full

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