Assessment of assumptions underlying models of prokaryotic pangenome evolution

Abstract Background The genomes of bacteria and archaea evolve by extensive loss and gain of genes which, for any group of related prokaryotic genomes, result in the formation of a pangenome with the universal, asymmetrical U-shaped distribution of gene commonality. However, the evolutionary factors...

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Bibliographic Details
Main Authors: Itamar Sela, Yuri I. Wolf, Eugene V. Koonin
Format: Article
Language:English
Published: BMC 2021-02-01
Series:BMC Biology
Subjects:
Online Access:https://doi.org/10.1186/s12915-021-00960-2