EZH2 Phosphorylation Promotes Self-Renewal of Glioma Stem-Like Cells Through NF-κB Methylation

EZH2 Phosphorylation Promotes Self-Renewal of Glioma Stem-Like Cells Through NF-κB Methylation

Cancer stem-like cells (CSCs) is a cell population in glioma with capacity of self-renewal and is critical in glioma tumorigenesis. Parallels between CSCs and normal stem cells suggest that CSCs give rise to tumors. Oncogenic roles of maternal embryonic leucine-zipper kinase (MELK) and enhancer of z...

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Bibliographic Details
Main Authors: Hailong Liu, Youliang Sun, Xueling Qi, Renata E. Gordon, Jenny A. O'Brien, Hongyu Yuan, Junping Zhang, Zeyuan Wang, Mingshan Zhang, Yongmei Song, Chunjiang Yu, Chunyu Gu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Oncology
Subjects:
cancer stem-like cells
glioma
EZH2 phosphorylation
NF-κB methylation
self-renewal
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00641/full

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https://www.frontiersin.org/article/10.3389/fonc.2019.00641/full

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