CAPRIN1 Is Required for Control of Viral Replication Complexes by Interferon Gamma

CAPRIN1 Is Required for Control of Viral Replication Complexes by Interferon Gamma

ABSTRACT Replication complexes (RCs), formed by positive-strand (+) RNA viruses through rearrangements of host endomembranes, protect their replicating RNA from host innate immune defenses. We have shown that two evolutionarily conserved defense systems, autophagy and interferon (IFN), target viral...

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Bibliographic Details
Main Authors: Chaitanya Kurhade, Soowon Kang, Scott B. Biering, Seungmin Hwang, Glenn Randall
Format: Article
Language:English
Published: American Society for Microbiology 2023-06-01
Series:mBio
Subjects:
autophagy
interferon gamma
replication compartments
Online Access:https://journals.asm.org/doi/10.1128/mbio.00172-23

Internet

https://journals.asm.org/doi/10.1128/mbio.00172-23

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