Effect of inhibition of CBP-coactivated β-catenin-mediated Wnt signalling in uremic rats with vascular calcifications.

Effect of inhibition of CBP-coactivated β-catenin-mediated Wnt signalling in uremic rats with vascular calcifications.

Uremic vascular calcification is a regulated cell-mediated process wherein cells in the arterial wall transdifferentiate to actively calcifying cells resulting in a process resembling bone formation. Wnt signalling is established as a major driver for vessel formation and maturation and for embryoni...

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Bibliographic Details
Main Authors: Eva Gravesen, Anders Nordholm, Maria Mace, Marya Morevati, Estrid Høgdall, Carsten Nielsen, Andreas Kjær, Klaus Olgaard, Ewa Lewin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6075782?pdf=render

Internet

http://europepmc.org/articles/PMC6075782?pdf=render

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