Relative evolutionary rate inference in HyPhy with LEISR

Relative evolutionary rate inference in HyPhy with LEISR

We introduce LEISR (Likehood Estimation of Individual Site Rates, pronounced “laser”), a tool to infer relative evolutionary rates from protein and nucleotide data, implemented in HyPhy. LEISR is based on the popular Rate4Site (Pupko et al., 2002) approach for inferring relative site-wise evolutiona...

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Bibliographic Details
Main Authors: Stephanie J. Spielman, Sergei L. Kosakovsky Pond
Format: Article
Language:English
Published: PeerJ Inc. 2018-02-01
Series:PeerJ
Subjects:
Protein evolution
Comparative sequence analysis
Evolutionary rate
Phylogenetics
Online Access:https://peerj.com/articles/4339.pdf

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https://peerj.com/articles/4339.pdf

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