Anti-Her2 affibody-decorated arsenene nanosheets induce ferroptosis through depleting intracellular GSH to overcome cisplatin resistance

Anti-Her2 affibody-decorated arsenene nanosheets induce ferroptosis through depleting intracellular GSH to overcome cisplatin resistance

Abstract Ferroptosis, a form of regulated cell death induced by excessive accumulation of reactive oxygen species and lipid peroxidation, has recently attracted extensive attention due to its ability to effectively suppress tumors and overcome drug resistance. Unlike previously reported metal nanoma...

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Bibliographic Details
Main Authors: Peng He, Shenglin Xu, Zhaohua Miao, Yukang Que, Yu Chen, Sheng Li, Qiming Ma, Rui Yang, Wei Wei, Zhengbao Zha, Yong Hu
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Journal of Nanobiotechnology
Subjects:
Ferroptosis
Arsenene nanosheets
Chemotherapy
Cisplatin resistance
Osteosarcoma
Online Access:https://doi.org/10.1186/s12951-023-01963-7

Internet

https://doi.org/10.1186/s12951-023-01963-7

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