The canonical eIF4E isoform of C. elegans regulates growth, embryogenesis, and germline sex-determination

eIF4E plays a conserved role in initiating protein synthesis, but with multiple eIF4E isoforms present in many organisms, these proteins also adopt specialized functions. Previous RNAi studies showed that ife-3, encoding the sole canonical eIF4E isoform of Caenorhabditis elegans, is essential for vi...

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Bibliographic Details
Main Authors: Richard S. Mangio, SarahBeth Votra, David Pruyne
Format: Article
Language:English
Published: The Company of Biologists 2015-07-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/4/7/843