Differential and Common Signatures of miRNA Expression and Methylation in Childhood Central Nervous System Malignancies: An Experimental and Computational Approach

Epigenetic modifications are considered of utmost significance for tumor ontogenesis and progression. Especially, it has been found that miRNA expression, as well as DNA methylation plays a significant role in central nervous system tumors during childhood. A total of 49 resected brain tumors from c...

Full description

Bibliographic Details
Main Authors: George I. Lambrou, Myrto Poulou, Krinio Giannikou, Marios Themistocleous, Apostolos Zaravinos, Maria Braoudaki
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/21/5491