Integrated plasma proteomics and lung transcriptomics reveal novel biomarkers in idiopathic pulmonary fibrosis

Integrated plasma proteomics and lung transcriptomics reveal novel biomarkers in idiopathic pulmonary fibrosis

Abstract Background Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease with a significant unmet medical need. Development of transformational therapies for IPF is challenging in part to due to lack of robust predictive biomarkers of prognosis and treatment response. Importantly, circulating...

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Bibliographic Details
Main Authors: Pitchumani Sivakumar, Ron Ammar, John Ryan Thompson, Yi Luo, Denis Streltsov, Mary Porteous, Carly McCoubrey, Edward Cantu, Michael F. Beers, Gabor Jarai, Jason D. Christie
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Respiratory Research
Subjects:
Idiopathic pulmonary fibrosis
Biomarkers
Chemokines
Mast cells
Extracellular matrix
Online Access:https://doi.org/10.1186/s12931-021-01860-3

Internet

https://doi.org/10.1186/s12931-021-01860-3

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