Recombinant Expression in <i>Pichia pastoris</i> System of Three Potent Kv1.3 Channel Blockers: Vm24, Anuroctoxin, and Ts6

Recombinant Expression in <i>Pichia pastoris</i> System of Three Potent Kv1.3 Channel Blockers: Vm24, Anuroctoxin, and Ts6

The Kv1.3 channel has become a therapeutic target for the treatment of various diseases. Several Kv1.3 channel blockers have been characterized from scorpion venom; however, extensive studies require amounts of toxin that cannot be readily obtained directly from venoms. The <i>Pichia pastoris&...

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Bibliographic Details
Main Authors: Jesús Borrego, Muhammad Umair Naseem, Al Nasar Ahmed Sehgal, Lipsa Rani Panda, Kashmala Shakeel, Attila Gaspar, Cynthia Nagy, Zoltan Varga, Gyorgy Panyi
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Journal of Fungi
Subjects:
<i>Pichia pastoris</i>
recombinant peptides
scorpion venoms
Kv1.3 blockers
Online Access:https://www.mdpi.com/2309-608X/8/11/1215

Internet

https://www.mdpi.com/2309-608X/8/11/1215

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