Impact of nucleic acid and methylated H3K9 binding activities of Suv39h1 on its heterochromatin assembly
SUV39H is the major histone H3 lysine 9 (H3K9)-specific methyltransferase that targets pericentric regions and is crucial for assembling silent heterochromatin. SUV39H recognizes trimethylated H3K9 (H3K9me3) via its chromodomain (CD), and enriched H3K9me3 allows SUV39H to target specific chromosomal...
| المؤلفون الرئيسيون: | , , , , , , , , |
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| التنسيق: | مقال |
| اللغة: | English |
| منشور في: |
eLife Sciences Publications Ltd
2017-08-01
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| سلاسل: | eLife |
| الموضوعات: | |
| الوصول للمادة أونلاين: | https://elifesciences.org/articles/25317 |