iPSC-Derived Microglia as a Model to Study Inflammation in Idiopathic Parkinson’s Disease

iPSC-Derived Microglia as a Model to Study Inflammation in Idiopathic Parkinson’s Disease

Parkinson’s disease (PD) is a neurodegenerative disease with unknown cause in the majority of patients, who are therefore considered “idiopathic” (IPD). PD predominantly affects dopaminergic neurons in the substantia nigra pars compacta (SNpc), yet the pathology is not limited to this cell type. Adv...

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Bibliographic Details
Main Authors: Katja Badanjak, Patrycja Mulica, Semra Smajic, Sylvie Delcambre, Leon-Charles Tranchevent, Nico Diederich, Thomas Rauen, Jens C. Schwamborn, Enrico Glaab, Sally A. Cowley, Paul M. A. Antony, Sandro L. Pereira, Carmen Venegas, Anne Grünewald
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
microglia
iPSC
neuroinflammation
idiopathic Parkinson’s disease
disease modeling
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.740758/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.740758/full

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