Cerebral Microvascular Senescence and Inflammation in Diabetes

Stress-induced premature senescence can contribute to the accelerated metabolic aging process in diabetes. Progressive accumulation of senescent cells in the brain, especially those displaying the harmful inflammatory senescence-associated secretory phenotype (SASP), may lead to cognitive impairment...

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Bibliographic Details
Main Authors: Ashley Phoenix, Raghavendar Chandran, Adviye Ergul
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.864758/full