Dose-escalated radiotherapy to 82 Gy for prostate cancer following insertion of a peri-rectal hydrogel spacer: 3-year outcomes from a phase II trial

Dose-escalated radiotherapy to 82 Gy for prostate cancer following insertion of a peri-rectal hydrogel spacer: 3-year outcomes from a phase II trial

Abstract Background Dose-escalation to above 80 Gy during external beam radiotherapy for localised prostate cancer leads to improved oncological outcomes but also substantially increased rectal toxicity. The aim of this study was to demonstrate the safety and efficacy of escalating the dose to 82 Gy...

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Bibliographic Details
Main Authors: Andrew W. See, Patrick Bowden, Geoffrey Wells, Sree Appu, Nathan Lawrentschuk, Peter Liodakis, Chloe Pandeli, Yolanda Aarons, Lloyd M. L. Smyth, Dean P. McKenzie
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Radiation Oncology
Subjects:
Dose-escalation
Hydrogel
Prostate cancer
Radiotherapy
Rectum
Toxicity
Online Access:https://doi.org/10.1186/s13014-022-02103-5

Internet

https://doi.org/10.1186/s13014-022-02103-5

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