TDO2‐augmented fibroblasts secrete EVs enriched in immunomodulatory Y‐derived small RNA

TDO2‐augmented fibroblasts secrete EVs enriched in immunomodulatory Y‐derived small RNA

Abstract Mounting evidence implicates extracellular vesicles (EVs) factors as mediators of cell therapy. Cardiosphere‐derived cells are cardiac‐derived cells with tissue reparative capacity. Activation of a downstream target of wnt/β‐catenin signalling, tryptophan 2,3 dioxygenase (TDO2) renders ther...

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Bibliographic Details
Main Authors: Alessandra Ciullo, Kiel Peck, Xaviar Jones, Shukuro Yamaguchi, Ashley Anne Morris, Arati Naveen Kumar, Liang Li, Jamie Lee, Rodrigo Miguel dos Santos, Eugenio Cingolani, Ahmed Gamal Ibrahim
Format: Article
Language:English
Published: Wiley 2023-02-01
Series:Journal of Extracellular Biology
Subjects:
extracellular vesicles
inflammation
macrophages
myocardial infarction
small RNA
TDO2
Online Access:https://doi.org/10.1002/jex2.73

Internet

https://doi.org/10.1002/jex2.73

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