Targeting MDR1-P-glycoprotein (MDR1-Pgp) in immunochemotherapy of acute myeloid leukemia (AML)

BACKGROUND: Monoclonal antibodies represent the fastest growing sector of pharmaceutical biotechnology and a number of antibody-based biopharmaceuticals have been approved for cancer treatment. However, in many cases the antibodies used for the treatment of tumors offer only a modest survival benefi...

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Bibliographic Details
Main Author: Maurizio Cianfriglia
Format: Article
Language:English
Published: Istituto Superiore di Sanità 2013-06-01
Series:Annali dell'Istituto Superiore di Sanità
Subjects:
Online Access:http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0021-25712013000200012&lng=en&tlng=en