Antifibrinolytic role of a bee venom serine protease inhibitor that acts as a plasmin inhibitor.

Bee venom is a rich source of pharmacologically active substances. In this study, we identified a bumblebee (Bombus ignitus) venom Kunitz-type serine protease inhibitor (Bi-KTI) that acts as a plasmin inhibitor. Bi-KTI showed no detectable inhibitory effect on factor Xa, thrombin, or tissue plasmino...

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Bibliographic Details
Main Authors: Young Moo Choo, Kwang Sik Lee, Hyung Joo Yoon, Yuling Qiu, Hu Wan, Mi Ri Sohn, Hung Dae Sohn, Byung Rae Jin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3281132?pdf=render