Two-Dimensional N-Glycan Distribution Mapping of Hepatocellular Carcinoma Tissues by MALDI-Imaging Mass Spectrometry

Two-Dimensional N-Glycan Distribution Mapping of Hepatocellular Carcinoma Tissues by MALDI-Imaging Mass Spectrometry

A new mass spectrometry imaging approach to simultaneously map the two-dimensional distribution of N-glycans in tissues has been recently developed. The method uses Matrix Assisted Laser Desorption Ionization Imaging Mass Spectrometry (MALDI-IMS) to spatially profile the location and distribution o...

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Bibliographic Details
Main Authors: Thomas W. Powers, Stephanie Holst, Manfred Wuhrer, Anand S. Mehta, Richard R. Drake
Format: Article
Language:English
Published: MDPI AG 2015-10-01
Series:Biomolecules
Subjects:
N-linked glycosylation
formalin-fixed paraffin-embedded tissue
hepatocellular carcinoma
MALDI imaging mass spectrometry
glycoprotein
Online Access:http://www.mdpi.com/2218-273X/5/4/2554

Internet

http://www.mdpi.com/2218-273X/5/4/2554

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