Attachment site selection and identity in Bxb1 serine integrase-mediated site-specific recombination.

Phage-encoded serine integrases mediate directionally regulated site-specific recombination between short attP and attB DNA sites without host factor requirements. These features make them attractive for genome engineering and synthetic genetics, although the basis for DNA site selection is poorly u...

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Bibliographic Details
Main Authors: Shweta Singh, Pallavi Ghosh, Graham F Hatfull
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-05-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3642061?pdf=render