Human Claudin-7 cis-Interactions Are Not Crucial for Membrane-Membrane (Trans-) Interactions

Human Claudin-7 cis-Interactions Are Not Crucial for Membrane-Membrane (Trans-) Interactions

Human Claudin-7 (Cldn7) is a member of the Claudin (Cldn) superfamily. In vivo, these proteins form tight junctions, which establish constricted connections between cells. Cldns oligomerize within the membrane plane (= cis-interaction), and also interact with Cldns from adjacent cells (= trans-inter...

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Bibliographic Details
Main Authors: Lena Ahlswede, Carmen Siebenaller, Benedikt Junglas, Nadja Hellmann, Dirk Schneider
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Molecular Biosciences
Subjects:
claudin
tight junction
heterologous expression
proteoliposomes
atomic force microscopy
membrane protein
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.908383/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2022.908383/full

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