RocA Regulates Phosphatase Activity of Virulence Sensor CovS of Group A <italic toggle="yes">Streptococcus</italic> in Growth Phase- and pH-Dependent Manners
ABSTRACT The control of the virulence response regulator and sensor (CovR-CovS) two-component regulatory system in group A Streptococcus (GAS) strains regulates more than 15% of gene expression and has critical roles in invasive GAS infection. The membrane-embedded CovS has kinase and phosphatase ac...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2020-06-01
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Series: | mSphere |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/mSphere.00361-20 |