NAT10‐mediated ac4C‐modified ANKZF1 promotes tumor progression and lymphangiogenesis in clear‐cell renal cell carcinoma by attenuating YWHAE‐driven cytoplasmic retention of YAP1

NAT10‐mediated ac4C‐modified ANKZF1 promotes tumor progression and lymphangiogenesis in clear‐cell renal cell carcinoma by attenuating YWHAE‐driven cytoplasmic retention of YAP1

Abstract Background Lymphatic metastasis is one of the most common metastatic routes and indicates a poor prognosis in clear‐cell renal cell carcinoma (ccRCC). N‐acetyltransferase 10 (NAT10) is known to catalyze N4‐acetylcytidine (ac4C) modification of mRNA and participate in many cellular processes...

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Bibliographic Details
Main Authors: Daojia Miao, Jian Shi, Qingyang Lv, Diaoyi Tan, Chuanyi Zhao, Zhiyong Xiong, Xiaoping Zhang
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:Cancer Communications
Subjects:
clear‐cell renal cell carcinoma
N4‐acetylcytidine
N‐acetyltransferase 10
YAP1 nuclear import
Online Access:https://doi.org/10.1002/cac2.12523

Internet

https://doi.org/10.1002/cac2.12523

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