Isolation of human monoclonal antibodies to the envelope e2 protein of hepatitis C virus and their characterization.

Isolation of human monoclonal antibodies to the envelope e2 protein of hepatitis C virus and their characterization.

We isolated and characterized two human monoclonal antibodies to the envelope E2 protein of hepatitis C virus (HCV). Lymphoblastoid cell lines stably producing antibodies were obtained by immortalizing peripheral blood mononuclear cells of a patient with chronic hepatitis C using Epstein-Barr virus....

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Bibliographic Details
Main Authors: Yohko K Shimizu, Minako Hijikata, Masamichi Oshima, Kazufumi Shimizu, Harvey J Alter, Robert H Purcell, Hiroshi Yoshikura, Hak Hotta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3567033?pdf=render

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http://europepmc.org/articles/PMC3567033?pdf=render

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