Emodin Attenuates Lipopolysaccharide-Induced Acute Liver Injury via Inhibiting the TLR4 Signaling Pathway in vitro and in vivo

Emodin Attenuates Lipopolysaccharide-Induced Acute Liver Injury via Inhibiting the TLR4 Signaling Pathway in vitro and in vivo

Aims: Emodin is an anthraquinone with potential anti-inflammatory properties. However, the possible molecular mechanisms and protective effects of emodin are not clear. The objective of this study was to investigate the possible molecular mechanisms and protective effects of emodin on lipopolysaccha...

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Bibliographic Details
Main Authors: Yan Ding, Pan Liu, Zhi-Lin Chen, Shao-Jun Zhang, You-Qin Wang, Xin Cai, Lei Luo, Xuan Zhou, Lei Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Pharmacology
Subjects:
emodin
lipopolysaccharide
TLR4
acute liver injury
signaling pathway
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00962/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.00962/full

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