Genome-Wide siRNA Screen Identifies Complementary Signaling Pathways Involved in <italic toggle="yes">Listeria</italic> Infection and Reveals Different Actin Nucleation Mechanisms during <italic toggle="yes">Listeria</italic> Cell Invasion and Actin Comet Tail Formation
ABSTRACT Listeria monocytogenes enters nonphagocytic cells by a receptor-mediated mechanism that is dependent on a clathrin-based molecular machinery and actin rearrangements. Bacterial intra- and intercellular movements are also actin dependent and rely on the actin nucleating Arp2/3 complex, which...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Society for Microbiology
2015-07-01
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| Series: | mBio |
| Online Access: | https://journals.asm.org/doi/10.1128/mBio.00598-15 |